Metodología para el seguimiento de los accidentes de trabajo graves y mortales de una ARL en Colombia

The Colombian legislation through the resolution 1401 of 2007 and the act 1295 of 1994 establishes the follow– up to the fulfillment of the recommendations derived of fatal accidents as an obligation for the risk management company (named in Colombia ARL). Objective: this research approaches the process of follow-up of the actions derived from the causal analysis of the serious and fatal work accidents in regional place of a Colombian ARL. Methods: for an initial diagnosis, the process of follow – up was characterized from the perspective of stakeholders involved through the application of tools of quantitative and qualitative analysis. Such as survey and systematic observation whose results generated a SWOT matrix and a flow chart. Results: the generated results allowed constructing a methodology articulated to some offers of improvement. For its construction this methodology uses different tools like Hierarchic Analysis of Processes (AHP) applied to a group of experts. Management of processes and time study. To validate the designed methodology we were implemented some tools in a pilot test in which follow-up is realized to the recommendations of punctual work accidents. Conclusion: Is important to emphasize that the methodology designed. in addition to formalizing the process. is going to impact both economically and the relationship person-hours by reducing operating times and expected on the long term its promoting the prevention of accidents at work by the same causes.La legislación Colombiana a través de la resolución 1401-2007 y el decreto Ley 1295-1994 establece el seguimiento al cumplimiento de las recomendaciones derivadas de la investigación de los accidentes de trabajo graves y mortales como una obligación para las ARLs y dado el potencial aumento en la ocurrencia de estos casos. se ha hecho necesario incorporar diferentes procedimientos para dar cumplimiento al seguimiento de este tipo de eventos que repercuten a todos los actores implicados (Empleadores. ARL. Trabajadores. entre otros). Objetivo: Analizar el proceso de seguimiento de las acciones derivadas del análisis causal de los accidentes de trabajo graves y mortales de una ARL Colombiana. Métodos: Descriptivo transversal, la muestra estuvo conformada por 51 actores involucrados en el proceso. Como método de recolección de información se utilizó una encuesta y la observación, se utilizó análisis cuantitativo y cualitativo. Resultados: Los resultados generados (matriz DOFA y flujograma del proceso) permitieron construir una metodología articulada a unas propuestas de mejora haciendo uso de herramientas entre las que se encuentran el Análisis Jerárquico de Procesos (AHP siglas en inglés) aplicado a grupo de expertos, gestión de procesos y estudio de tiempos. Finalmente se implementaron algunas. Conclusión: La metodología diseñada evidenció un impacto en la relación horas–hombre al disminuir tiempos de operación y se espera impacto en el largo plazo al fomentar la prevención de accidentes de trabajo por las mismas causas derivadas del trabajo

Differential antibody response against conformational and linear epitopes of the L1 protein from human papillomavirus types 16/18 is generated in vaccinated woman or with different exposures to the virus

Antibodies against human papillomavirus (HPV) L1 protein are associated to past infections and related to the evolution of the disease, while antibodies against L1 virus like particles (VLPs-L1) are used to follow the neutralizing immune response in vaccinated women. In this study, sera antibodies against conformational and linear epitopes of L1 protein from HPV16/18 were evaluated to discriminate HPV vaccinated women from those naturally infected or with uterine cervical lesions. The VLPs-L1 from HPV16/18 generated in baculovirus were purified by CsCl gradient and linear L1 protein obtained by denature VLPs. Serum antibodies against VLPs-L1 and L1 from vaccinated women or with different exposures to the virus were measured by ELISA. Regresion and ROC analysis were carried out to evaluete the test performance to discriminate the different women populations. The results showed that antibodies against VLPs-L1-16/18 highly associated with vaccinated women (OR=2.11e+08 and 57.74, respectively), but not associations were observed with natural infected women or with cervical lesions. However, antibodies against L1-16/18 showed high associations with vaccinated women (OR= 101.33 and 37.91, respectively) (p≤ 0.05), but also associations of these antibodies were observed with the cervical cancer (CC) group (OR= 3.33 and 5.65, respectively). The ROC analysis showed that antibodies against VLPs-L1 and L1 16/18 were highly effective to detect vaccinated women (AUC= 0.96, 0.91. 0.80 and 0.78, respectively), with high sensitivity for HPV16 (100% and 86.3%), and moderate for HPV18 (63.6%). However, anti-L1 antibodies had the best test performance to discriminate the cervical intraepithelial neoplasia grade 3 (CIN3)/CC group from controls (AUC= 0.67 HPV16 and 0.63 HPV18), with low sensitivity (15% to 20%, respectively) and high specificity (96% and 92%, respectively). In conclusion, our results suggested that anti-VLPs-L1 16/18 antibodies are highly efficient to detect vaccinated women, but anti-L1 antibodies are better to discriminate CIN3/CC among the general population

Metodología para el seguimiento de los accidentes de trabajo graves y mortales de una ARL en Colombia

The Colombian legislation through the resolution 1401 of 2007 and the act 1295 of 1994 establishes the follow– up to the fulfillment of the recommendations derived of fatal accidents as an obligation for the risk management company (named in Colombia ARL). Objective: this research approaches the process of follow-up of the actions derived from the causal analysis of the serious and fatal work accidents in regional place of a Colombian ARL. Methods: for an initial diagnosis, the process of follow – up was characterized from the perspective of stakeholders involved through the application of tools of quantitative and qualitative analysis. Such as survey and systematic observation whose results generated a SWOT matrix and a flow chart. Results: the generated results allowed constructing a methodology articulated to some offers of improvement. For its construction this methodology uses different tools like Hierarchic Analysis of Processes (AHP) applied to a group of experts. Management of processes and time study. To validate the designed methodology we were implemented some tools in a pilot test in which follow-up is realized to the recommendations of punctual work accidents. Conclusion: Is important to emphasize that the methodology designed. in addition to formalizing the process. is going to impact both economically and the relationship person-hours by reducing operating times and expected on the long term its promoting the prevention of accidents at work by the same causes.La legislación Colombiana a través de la resolución 1401-2007 y el decreto Ley 1295-1994 establece el seguimiento al cumplimiento de las recomendaciones derivadas de la investigación de los accidentes de trabajo graves y mortales como una obligación para las ARLs y dado el potencial aumento en la ocurrencia de estos casos. se ha hecho necesario incorporar diferentes procedimientos para dar cumplimiento al seguimiento de este tipo de eventos que repercuten a todos los actores implicados (Empleadores. ARL. Trabajadores. entre otros). Objetivo: Analizar el proceso de seguimiento de las acciones derivadas del análisis causal de los accidentes de trabajo graves y mortales de una ARL Colombiana. Métodos: Descriptivo transversal, la muestra estuvo conformada por 51 actores involucrados en el proceso. Como método de recolección de información se utilizó una encuesta y la observación, se utilizó análisis cuantitativo y cualitativo. Resultados: Los resultados generados (matriz DOFA y flujograma del proceso) permitieron construir una metodología articulada a unas propuestas de mejora haciendo uso de herramientas entre las que se encuentran el Análisis Jerárquico de Procesos (AHP siglas en inglés) aplicado a grupo de expertos, gestión de procesos y estudio de tiempos. Finalmente se implementaron algunas. Conclusión: La metodología diseñada evidenció un impacto en la relación horas–hombre al disminuir tiempos de operación y se espera impacto en el largo plazo al fomentar la prevención de accidentes de trabajo por las mismas causas derivadas del trabajo

Metodología para el seguimiento de los accidentes de trabajo graves y mortales de una ARL en Colombia

La legislación Colombiana a través de la resolución 1401-2007 y el decreto Ley 1295-1994 establece el seguimiento al cumplimiento de las recomendaciones derivadas de la investigación de los accidentes de trabajo graves y mortales como una obligación para las ARLs y dado el potencial aumento en la ocurrencia de estos casos. se ha hecho necesario incorporar diferentes procedimientos para dar cumplimiento al seguimiento de este tipo de eventos que repercuten a todos los actores implicados (Empleadores. ARL. Trabajadores. entre otros). Objetivo: Analizar el proceso de seguimiento de las acciones derivadas del análisis causal de los accidentes de trabajo graves y mortales de una ARL Colombiana. Métodos: Descriptivo transversal, la muestra estuvo conformada por 51 actores involucrados en el proceso. Como método de recolección de información se utilizó una encuesta y la observación, se utilizó análisis cuantitativo y cualitativo. Resultados: Los resultados generados (matriz DOFA y flujograma del proceso) permitieron construir una metodología articulada a unas propuestas de mejora haciendo uso de herramientas entre las que se encuentran el Análisis Jerárquico de Procesos (AHP siglas en inglés) aplicado a grupo de expertos, gestión de procesos y estudio de tiempos. Finalmente se implementaron algunas. Conclusión: La metodología diseñada evidenció un impacto en la relación horas–hombre al disminuir tiempos de operación y se espera impacto en el largo plazo al fomentar la prevención de accidentes de trabajo por las mismas causas derivadas del trabajo.The Colombian legislation through the resolution 1401 of 2007 and the act 1295 of 1994 establishes the follow– up to the fulfillment of the recommendations derived of fatal accidents as an obligation for the risk management company (named in Colombia ARL). Objective: this research approaches the process of follow-up of the actions derived from the causal analysis of the serious and fatal work accidents in regional place of a Colombian ARL. Methods: for an initial diagnosis, the process of follow – up was characterized from the perspective of stakeholders involved through the application of tools of quantitative and qualitative analysis. Such as survey and systematic observation whose results generated a SWOT matrix and a flow chart. Results: the generated results allowed constructing a methodology articulated to some offers of improvement. For its construction this methodology uses different tools like Hierarchic Analysis of Processes (AHP) applied to a group of experts. Management of processes and time study. To validate the designed methodology we were implemented some tools in a pilot test in which follow-up is realized to the recommendations of punctual work accidents. Conclusion: Is important to emphasize that the methodology designed. in addition to formalizing the process. is going to impact both economically and the relationship person-hours by reducing operating times and expected on the long term its promoting the prevention of accidents at work by the same causes

Metodología para el seguimiento de los accidentes de trabajo graves y mortales de una ARL en Colombia

La legislación Colombiana a través de la resolución 1401-2007 y el decreto Ley 1295-1994 establece el seguimiento al cumplimiento de las recomendaciones derivadas de la investigación de los accidentes de trabajo graves y mortales como una obligación para las ARLs y dado el potencial aumento en la ocurrencia de estos casos. se ha hecho necesario incorporar diferentes procedimientos para dar cumplimiento al seguimiento de este tipo de eventos que repercuten a todos los actores implicados (Empleadores. ARL. Trabajadores. entre otros). Objetivo: Analizar el proceso de seguimiento de las acciones derivadas del análisis causal de los accidentes de trabajo graves y mortales de una ARL Colombiana. Métodos: Descriptivo transversal, la muestra estuvo conformada por 51 actores involucrados en el proceso. Como método de recolección de información se utilizó una encuesta y la observación, se utilizó análisis cuantitativo y cualitativo. Resultados: Los resultados generados (matriz DOFA y flujograma del proceso) permitieron construir una metodología articulada a unas propuestas de mejora haciendo uso de herramientas entre las que se encuentran el Análisis Jerárquico de Procesos (AHP siglas en inglés) aplicado a grupo de expertos, gestión de procesos y estudio de tiempos. Finalmente se implementaron algunas. Conclusión: La metodología diseñada evidenció un impacto en la relación horas–hombre al disminuir tiempos de operación y se espera impacto en el largo plazo al fomentar la prevención de accidentes de trabajo por las mismas causas derivadas del trabajo

Study of water vapour permeability of protein and gum-based edible films by a photothermal method

The water vapour permeability of protein and gum-based edible films was studied by means of a photothermal method. The films were prepared with two basic ingredients, whey protein concentrate and mesquite gum, according to the proportions 75:25, 50:50, 25:75, and 0:100 (weight:weight). The water vapour diffusion coefficient of the analyzed films was found within the interval $0.37 \times 10^{-6}$ to $2.04 \times 10^{-6}$ cm$^2$/s, increasing linearly by increasing the mesquite gum composition in the films. The incorporation of mesquite gum in films produces less effective moisture barriers due to its highly hydrophilic property

44. Impact of Nursing Home (NH) Universal Decolonization and COVID Prevention Training on COVID-19 Burden During the 2020-2021 Winter Surge in Orange County (OC), California (CA)

Abstract Background OC is the 6th largest U.S. county with 70 NHs. Universal decolonization (chlorhexidine for routine bathing, and twice daily nasal iodophor Mon-Fri every other week) was adopted in 24 NHs prior to the COVID-19 pandemic, and 12 NHs (11 of those adopting decolonization) participated in a COVID prevention training program with a rolling launch from July-Sept 2020. We evaluated the impact of these initiatives on staff and resident COVID cases. Methods We conducted a quasi-experimental study of the impact of decolonization and COVID prevention training on staff and resident COVID cases during the CA winter surge (11/16/20-1/31/21), when compared to non-participating NHs. Decolonization NHs received weekly visits for encouraging adherence during the pandemic, and NHs in the COVID training program received 3 in-person training sessions for all work shifts plus weekly feedback about adherence to hand hygiene, masking, and breakroom safety using video monitoring. We calculated incident 1) staff COVID cases, 2) resident COVID cases, and 3) resident COVID deaths adjusting for NH average daily census. We assessed impact of initiatives on these outcomes using linear mixed effects models testing the interaction between any training participation and calendar date when clustering by NH. Because of the overlap of the two initiatives, we evaluated ‘any training’ vs ‘no training.’ Results 63 NHs had available data. 24 adopted universal decolonization, 12 received COVID training (11 of which participated in decolonization), and 38 were not enrolled in either. During the winter surge, the 63 NHs experienced 1867 staff COVID cases, 2186 resident COVID cases, and 251 resident deaths due to COVID, corresponding to 29.6, 34.7, and 4.0 events per NH, respectively. In NHs participating in either initiative, staff COVID cases were reduced by 31% (OR=0.69 (0.52, 0.92), P=0.01), resident COVID cases were reduced by 43% (OR=0.57 (0.39, 0.82), P=0.003), and resident deaths were reduced (non-significantly) by 26% (OR=0.74 (0.46, 1.21), P=0.23). The grey box represents the California COVID-19 winter surge (11/16/20-1/31/21). Incident and cumulative COVID-19 cases and deaths for each nursing home were divided by the nursing home’s average daily census and multiplied by 100, representing events per 100 beds, which were aggregated across groups. Conclusion NHs are vulnerable to COVID-19 outbreaks. A universal decolonization and COVID prevention training initiative in OC, CA significantly reduced staff and resident COVID cases in this high-risk care setting. Disclosures Gabrielle Gussin, MS, Medline (Other Financial or Material Support, Conducted studies in which participating hospitals and nursing homes received contributed antiseptic and cleaning products)Stryker (Sage) (Other Financial or Material Support, Conducted studies in which participating hospitals and nursing homes received contributed antiseptic products)Xttrium (Other Financial or Material Support, Conducted studies in which participating hospitals and nursing homes received contributed antiseptic products) Raveena Singh, MA, Medline (Other Financial or Material Support, Conducted studies in which participating hospitals and nursing homes received contributed antiseptic and cleaning products)Stryker (Sage) (Other Financial or Material Support, Conducted studies in which participating hospitals and nursing homes received contributed antiseptic products)Xttrium (Other Financial or Material Support, Conducted studies in which participating hospitals and nursing homes received contributed antiseptic products) Shruti K. Gohil, MD, MPH, Medline (Other Financial or Material Support, Co-Investigator in studies in which participating hospitals and nursing homes received contributed antiseptic and cleaning products)Molnycke (Other Financial or Material Support, Co-Investigator in studies in which participating hospitals and nursing homes received contributed antiseptic and cleaning products)Stryker (Sage) (Other Financial or Material Support, Co-Investigator in studies in which participating hospitals and nursing homes received contributed antiseptic and cleaning products) Raheeb Saavedra, AS, Medline (Other Financial or Material Support, Conducted studies in which participating hospitals and nursing homes received contributed antiseptic and cleaning products)Stryker (Sage) (Other Financial or Material Support, Conducted studies in which participating hospitals and nursing homes received contributed antiseptic products)Xttrium (Other Financial or Material Support, Conducted studies in which participating hospitals and nursing homes received contributed antiseptic products) Robert Pedroza, BS, Medline (Other Financial or Material Support, Conducted studies in which participating hospitals and nursing homes received contributed antiseptic and cleaning products) Chase Berman, BS, Medline (Other Financial or Material Support, Conducted studies in which participating hospitals and nursing homes received contributed antiseptic and cleaning products) Susan S. Huang, MD, MPH, Medline (Other Financial or Material Support, Conducted studies in which participating hospitals and nursing homes received contributed antiseptic and cleaning products)Molnlycke (Other Financial or Material Support, Conducted studies in which participating hospitals and nursing homes received contributed antiseptic and cleaning products)Stryker (Sage) (Other Financial or Material Support, Conducted studies in which participating hospitals and nursing homes received contributed antiseptic and cleaning products)Xttrium (Other Financial or Material Support, Conducted studies in which participating hospitals and nursing homes received contributed antiseptic and cleaning products

Multicenter evaluation of contamination of the healthcare environment near patients with Candida auris skin colonization – ERRATUM

[This corrects the article DOI: 10.1017/ash.2022.205.]